Important Safety Information

Prescription Medications Require Medical Evaluation

Certain medications require a valid prescription from a licensed healthcare provider affiliated with Remedora or LocumTele Medical Group. Before starting any prescription medication, you must have a consultation with a licensed provider who will evaluate whether the medication is appropriate for your health status and medical history. Treatment approval is not guaranteed.

Medication Risks and Side Effects

Prescription medications may involve serious health risks, side effects, and complications. Before beginning treatment, carefully review all available safety information provided by your healthcare provider and pharmacy. Discuss with your provider any concerns about potential risks, warnings, contraindications, drug interactions, or adverse effects. If you have questions about your specific medication or health condition, contact your healthcare provider directly.

Reporting Adverse Events

If you experience any adverse reactions, unexpected side effects, or complications related to your treatment, report them immediately to your healthcare provider and dispensing pharmacy. You may also report suspected adverse events directly to the FDA:

FDA MedWatch Hotline: 1-800-FDA-1088 FDA MedWatch Online: www.fda.gov/medwatch

Medical Emergencies

If you believe you are experiencing a medical emergency, call 911 or go to the nearest emergency room immediately. Do not wait for a telehealth consultation.

BioLume's Role

BioLume Rx provides administrative, technology, and platform support services only. BioLume Rx does not practice medicine, provide medical advice, diagnose conditions, prescribe medications, or operate as a pharmacy. All medical evaluations, prescribing decisions, treatment recommendations, and safety determinations are made exclusively by independent licensed healthcare providers affiliated with Remedora or LocumTele Medical Group. BioLume Rx is not responsible for medical outcomes, treatment effectiveness, or adverse events.

Telehealth Limitations

Telehealth consultations have limitations compared to in-person medical evaluation. Your healthcare provider will determine whether your condition requires in-person examination or if telehealth is appropriate. Certain conditions or circumstances may require in-person care.

Trademark Ownership and Brand Disclaimers

BioLume Rx does not manufacture, own, or control any brand-name prescription medications, including but not limited to Ozempic®, Wegovy®, Mounjaro®, Zepbound®, or any other branded pharmaceutical products. These are registered trademarks of their respective manufacturers.

BioLume Rx is not affiliated with, endorsed by, or sponsored by any pharmaceutical manufacturer, including Novo Nordisk A/S, Eli Lilly and Company, or any other drug company. BioLume Rx does not claim ownership of any brand-name or FDA-approved medications referenced on this website or platform.

References to brand-name medications on the BioLume Rx platform are for informational purposes only and do not indicate that BioLume Rx manufactures, sells, or controls those medications. Any medications provided through BioLume Rx are sourced from licensed pharmacies and compounding facilities and are prescribed solely at the discretion of LocumTele Pharmacy Group with a licensed healthcare provider.

Important Safety Information regarding Compounded Semaglutide

Before Starting Semaglutide:

• Tell your healthcare provider about your complete medical history, including any history of:

• Kidney, liver, or pancreas problems

• Thyroid disease or thyroid cancer

• Gallstones or gallbladder disease

• Diabetic retinopathy (if you have type II diabetes)

• Severe gastrointestinal disease

• Depression, behavior changes, or suicidal thoughts

• Avoid alcohol while taking this medication

• Do not take this medication if pregnant, trying to become pregnant, or breastfeeding. Semaglutide may cause fetal harm. If you plan to become pregnant, stop this medication at least 2 months before trying to conceive.

• Use adequate contraception while taking this medication

• Diabetes medications may need adjustment. If you take insulin or other diabetes medications, discuss this with your prescribing doctor before starting semaglutide, as your doses may need to be lowered to reduce the risk of low blood sugar.

Drug Interactions

Compounded semaglutide can interact with alcohol and certain prescription and non-prescription medications. The risk of low blood sugar is increased when combined with insulin or insulin secretagogues (such as Glipizide, glimepiride, or glyburide). Discuss any potential medication adjustments with your healthcare provider.

Semaglutide delays stomach emptying and may affect how your body absorbs oral medications. If you take thyroid medication (such as levothyroxine), discuss the timing of your doses with your doctor, you may need to adjust when you take it.

If you take medications with narrow therapeutic windows (such as warfarin), your doctor should monitor drug levels closely while you are on semaglutide.

Please review the complete list of side effects, warnings, interactions, and additional information provided with your pharmacy's packaging.

Reporting Side Effects and Concerns

If you experience any adverse reactions, unexpected side effects, or complications related to semaglutide, report them immediately to:

• Your healthcare provider

• Your dispensing pharmacy

You may also report suspected adverse events directly to the FDA:

• FDA MedWatch Hotline: 1-800-FDA-1088

• FDA MedWatch Online: www.fda.gov/medwatch

Additional Important Notes

• Never share semaglutide with other people. This medication is prescribed for your specific health condition.

• Your healthcare provider is responsible for determining whether semaglutide is medically appropriate for your condition and for monitoring your progress.

• BioLume Rx facilitates access to semaglutide through partner pharmacies but does not provide medical advice, prescribing, or medical supervision. All medical decisions are made by your licensed healthcare provider.

Black Box Warning: Thyroid Risk

GLP-1 medications are contraindicated (not safe for) individuals with:

• A personal history of medullary thyroid carcinoma (thyroid cancer)

• A family history of medullary thyroid carcinoma

• Multiple endocrine neoplasia syndrome type 2 (MEN 2)

In animal studies, GLP-1s caused thyroid tumors, including thyroid cancer. It is not yet known whether they will cause thyroid tumors or cancer in humans. Do not take tirzepatide if you have ever had thyroid cancer. Notify your doctor immediately if you develop trouble swallowing, hoarseness, a lump or swelling in your neck, or shortness of breath.

Disclaimer: These statements have not been evaluated by the U.S. Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease or medical condition.

Important Safety Information regarding Tirzepatide

Before Starting Tirzepatide:

• Tell your healthcare provider about your complete medical history, including any history of:

• Kidney, liver, or pancreas problems

• Thyroid disease or thyroid cancer

• Gallstones or gallbladder disease

• Diabetic retinopathy (if you have type II diabetes)

• Severe gastrointestinal disease

• Depression, behavior changes, or suicidal thoughts

• Avoid alcohol while taking this medication

• Do not take this medication if pregnant, trying to become pregnant, or breastfeeding. Tirzepatide may cause fetal harm. If you plan to become pregnant, stop this medication at least 2 months before trying to conceive.

• Use adequate contraception while taking this medication. Tirzepatide may reduce the effectiveness of birth control pills. Discuss alternative contraception methods with your doctor and use backup contraception for 4 weeks after starting tirzepatide and for 4 weeks after each dose increase.

• Diabetes medications may need adjustment. If you take insulin or other diabetes medications, discuss this with your prescribing doctor before starting tirzepatide, as your doses may need to be lowered to reduce the risk of low blood sugar.

Common Side Effects

The most frequently reported side effects of compounded tirzepatide include:

• Nausea

• Diarrhea

• Vomiting

• Constipation

• Abdominal pain or indigestion

• Injection site reactions

• Fatigue

• Heartburn or belching

• Hair loss

• Allergic reactions

These side effects are not exhaustive. If you experience any persistent or bothersome side effects, discuss them with your healthcare provider for appropriate management and possible dose adjustment.

Drug Interactions

Compounded tirzepatide can interact with alcohol and certain prescription and non-prescription medications. The risk of low blood sugar is increased when combined with insulin or insulin secretagogues (such as Glipizide, glimepiride, or glyburide). Discuss any potential medication adjustments with your healthcare provider.

Tirzepatide delays stomach emptying and may affect how your body absorbs oral medications. If you take thyroid medication (such as levothyroxine), discuss the timing of your doses with your doctor, you may need to adjust when you take it.

If you take medications with narrow therapeutic windows (such as warfarin), your doctor should monitor drug levels closely while you are on tirzepatide.

Please review the complete list of side effects, warnings, interactions, and additional information provided with your pharmacy's packaging.

Reporting Side Effects and Concerns

If you experience any adverse reactions, unexpected side effects, or complications related to tirzepatide, report them immediately to:

• Your healthcare provider

• Your dispensing pharmacy

You may also report suspected adverse events directly to the FDA:

• FDA MedWatch Hotline: 1-800-FDA-1088

• FDA MedWatch Online: www.fda.gov/medwatch

Additional Important Notes

• Never share tirzepatide with other people**.** This medication is prescribed for your specific health condition.

• Your healthcare provider is responsible for determining whether tirzepatide is medically appropriate for your condition and for monitoring your progress.

• BioLume Rx facilitates access to tirzepatide through partner pharmacies but does not provide medical advice, prescribing, or medical supervision. All medical decisions are made by LocumTele Medical Group licensed provider group.

Disclaimer: These statements have not been evaluated by the U.S. Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease or medical condition.